{"title":"Endocrinology \u0026 Metabolism","description":null,"products":[{"product_id":"abc-of-diabetes","title":"ABC of Diabetes","description":"\u003cp\u003e\u003ci\u003eABC of Diabetes\u003c\/i\u003e provides primary care practitioners with a practical guide to all aspects of diabetes including the aetiology, diagnosis and management of Types 1 and 2 diabetes, detection and prevention, and the organization of care and support.\u003c\/p\u003e \u003cp\u003eAdvances in diabetes care take place at a rapid rate and this new edition is updated throughout to cover the latest evidence-based information for contemporary practice. A new chapter describes the management of severe and complex obesity complicated by diabetes and the management of patients through bariatric surgery.\u003c\/p\u003e \u003cp\u003eIt also covers the growing number of devices and digital technology, including health informatics, that can assist in diabetes care and provides evidence of their benefit. With more links to useful websites and resources online, it is now easier than ever to keep up-to-date with changes.\u003c\/p\u003e \u003cp\u003eDrawing on the professional and teaching experience of an expert author team, \u003ci\u003eABC of Diabetes\u003c\/i\u003e is an essential guide for general practice, primary care practitioners, diabetes specialist nurses, as well as for medical students and those training in diabetes as a specialty.\u003c\/p\u003e","brand":"None","offers":[{"title":"Paperback","offer_id":46160203251889,"sku":"9781118850534","price":68.95,"currency_code":"CAD","in_stock":false},{"title":"Kobo eBook","offer_id":46160203284657,"sku":"cfd2de63-e3b5-3bb0-95e1-6c138ca7244f","price":55.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0655\/8980\/5233\/files\/1_ed02bb43-9cab-4681-8a52-2e450b831da9.jpg?v=1763685679"},{"product_id":"environmental-pollution-and-type-2-diabetes-mellitus","title":"Environmental Pollution and Type 2 Diabetes Mellitus","description":"\u003ci\u003eEnvironmental Pollution and Type 2 Diabetes Mellitus\u003c\/i\u003eelucidates on the global impact of environmental pollution and how it increases diabetes mellitus. Swift urbanization and the industrial revolution have increased environmental pollution to a hazardous level. Environmental pollution is a leading risk factor for several well-known diseases. This book opens venues for students, physicians, researchers, the science community, and policymakers to enhance their knowledge about environmental pollution, weather conditions, climate change, and their impact on insulin resistance and mechanisms allied to Type 2 diabetes mellitus (T2DM).\u003cbr\u003e\u003cbr\u003eMoreover, this book will provide knowledge about the green space environment and its impact on T2DM.\u003cbr\u003e\u003cbr\u003e\u003cul\u003e\n\u003cli\u003eOffers unique scientific information, facts, and figures about environmental pollution and T2DM\u003c\/li\u003e\n\u003cli\u003eHighlights the air pollution condition of different countries on various continents and mechanisms allied to developing T2DM\u003c\/li\u003e\n\u003cli\u003eProvides information about countries highly polluted and countries less polluted, along with the epidemiological trends of T2DM\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"None","offers":[{"title":"Paperback","offer_id":46165828731057,"sku":"9780443216466","price":244.5,"currency_code":"CAD","in_stock":false},{"title":"Kobo eBook","offer_id":46165828763825,"sku":"a9e84cb4-ab1f-3e0e-878e-948c8c04485b","price":145.59,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0655\/8980\/5233\/files\/1_830532d1-4d29-4a0e-9b30-7114190a44a7.jpg?v=1762683141"},{"product_id":"essential-endocrinology-and-diabetes","title":"Essential Endocrinology and Diabetes","description":"\u003cp\u003e\u003cb\u003eThe \u003ci\u003eEssentials\u003c\/i\u003e are an international, best-selling series of textbooks, all of which are designed to support lecture series or themes on core topics within the health sciences. See www.wiley.com for further details.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003ci\u003eEssential Endocrinology and Diabetes\u003c\/i\u003e provides the accurate and up-to-date knowledge required for treating all areas of endocrinology and diabetes, covering the latest research, clinical guidelines, investigational methods, and therapies. This classic text explains the vital aspects of endocrine physiology in a succinct and easy-to-use format, with full-colour illustrations, clinical images, and case studies to assist readers in applying theory to practice.\u003c\/p\u003e \u003cp\u003eThe text covers the principles of endocrinology, clinical endocrinology, and clinical diabetes and obesity, and has been revised throughout to present the most recent developments in the field. The seventh edition includes new and updated material on the latest molecular techniques, approaches to clinical investigation and diagnostics, next generation sequencing technology, and positron emission tomography (PET). The treatment of type 1 diabetes and type 2 diabetes has been updated with clinical algorithms and reflects significant advances such as incretin-based therapies, SGLT2 inhibitors, the development of better insulins, and technologies that support self-management.\u003c\/p\u003e \u003cul\u003e \u003cli\u003eProvides students and practitioners with comprehensive and authoritative information on all major aspects of endocrine physiology\u003c\/li\u003e \u003cli\u003eCovers diagnosis, management, and complications of clinical disorders such as endocrine neoplasia, and type 1 diabetes and type 2 diabetes\u003c\/li\u003e \u003cli\u003eExplains the core principle of feedback regulation, which is vital for the correct interpretation of many clinical tests\u003c\/li\u003e \u003cli\u003eFeatures case histories, learning objectives, ‘recap’ links to chapter content, cross-referencing guides, key information boxes, and chapter summaries\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003e\u003ci\u003eEssential Endocrinology and Diabetes, Seventh Edition\u003c\/i\u003e is the ideal textbook for medical and biomedical students, junior doctors, and clinicians looking to refresh their knowledge of endocrine science.\u003c\/p\u003e \u003cp\u003eFor more information on the complete range of Wiley medical student and junior doctor publishing, please visit: \u003cb\u003ewww.wiley.com\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eTo receive automatic updates on Wiley books and journals, join our email list. Sign up today at \u003cb\u003ewww.wiley.com\/email\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eAll content reviewed by students for students\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eWiley Medical Education books are designed exactly for their intended audience. All of our books are developed in collaboration with students. This means that our books are always published with you, the student, in mind.\u003c\/p\u003e \u003cp\u003eIf you would like to be one of our student reviewers, go to \u003cb\u003ewww.reviewmedicalbooks.com\u003c\/b\u003e to find out more.\u003c\/p\u003e \u003cp\u003eThis title is also available as an e-book. For more details, please see \u003cb\u003ewww.wiley.com\/buy\/9781118763964\u003c\/b\u003e\u003c\/p\u003e","brand":"None","offers":[{"title":"Paperback","offer_id":46167354998961,"sku":"9781118763964","price":84.95,"currency_code":"CAD","in_stock":true},{"title":"Kobo eBook","offer_id":46167355031729,"sku":"cca764e0-c33d-3b54-b69b-57235e318c23","price":67.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0655\/8980\/5233\/files\/1_9d03d69c-7fc0-4b56-9c98-2e74638322ca.jpg?v=1763717739"},{"product_id":"endocrinology-and-diabetes","title":"Endocrinology and Diabetes","description":"\u003cp\u003e\u003cb\u003eBalancing depth and accessibility, \u003ci\u003eEndocrinology and Diabetes: Lecture Notes, 2nd Edition\u003c\/i\u003e, provides medical students and junior doctors with the key information needed to understand mechanisms of endocrine conditions.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eThis popular revision guide covers endocrine anatomy and physiology, scientific background, clinical presentations, diagnosis and management of various endocrine disorders. Clear and concise chapters focus on conditions commonly encountered in both clinical practice and assessments.\u003c\/p\u003e \u003cp\u003eNow in full colour, the second edition has been updated with further figures that demonstrate features of endocrine conditions.\u003c\/p\u003e \u003cul\u003e \u003cli\u003eFeatures enhanced and expanded coverage of all major topics within diabetes and endocrinology\u003c\/li\u003e \u003cli\u003eReflects the current knowledge base, evidence, and best practices in the field\u003c\/li\u003e \u003cli\u003eProvides easy access to the scientific background, presentation, diagnosis, and management of each condition\u003c\/li\u003e \u003cli\u003eOffers up-to-date information for those preparing for MRCP or endocrinology specialty exams\u003c\/li\u003e \u003cli\u003eIncludes boxed sections in every chapter highlighting key points to aid revision and recall\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003e\u003ci\u003eEndocrinology and Diabetes: Lecture Notes, 2nd Edition,\u003c\/i\u003e remains a must-have for medical students, specialist nurses, junior doctors, and trainees working on endocrinology rotations or preparing for the Specialty Certificate Examination in Endocrinology.\u003c\/p\u003e \u003cp\u003eFor more information on the complete range of Wiley medical student and junior doctor publishing, please visit: \u003cb\u003ewww.wiley.com\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eTo receive automatic updates on Wiley books and journals, join our email list. Sign up today at \u003cb\u003ewww.wiley.com\/email\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eThis new edition is also available as an e-book. For more details, please see \u003cb\u003ehttp:\/\/www.wiley.com\/buy\/9781118682241\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eAll content reviewed by students for students\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eWiley Medical Education books are designed exactly for their intended audience. All of our books are developed in collaboration with students. This means that our books are always published with you, the student, in mind.\u003c\/p\u003e \u003cp\u003eIf you would like to be one of our student reviewers, go to \u003cb\u003ewww.reviewmedicalbooks.com\u003c\/b\u003e to find out more.\u003c\/p\u003e","brand":"None","offers":[{"title":"Paperback","offer_id":46167357587633,"sku":"9781118682241","price":53.95,"currency_code":"CAD","in_stock":false},{"title":"Kobo eBook (2023)","offer_id":46167357620401,"sku":"97367e17-158e-3e5a-b7e7-d1bbf46b3bc5","price":43.99,"currency_code":"CAD","in_stock":true},{"title":"Kobo eBook (2013)","offer_id":46167357653169,"sku":"f60e7953-5e7b-3667-bb64-1e33aa36aa9b","price":49.95,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0655\/8980\/5233\/files\/1_7ea1b5d5-a63f-42de-91bd-2effa1586655.jpg?v=1763603442"},{"product_id":"the-power-of-hormones","title":"The Power of Hormones: The New Science of How Hormones Impact Every Aspect of Our Health","description":"\u003cb\u003eA fascinating, in-depth look at the crucial role that hormones play on human health at all ages and stages of our lives—written by one of the world’s foremost experts.\u003c\/b\u003e\u003cbr\u003e\u003cbr\u003e\u003ci\u003e“Hormones are the conductors of our body’s orchestra.” \u003c\/i\u003e—Max Nieuwdorp\u003cbr\u003e \u003cbr\u003eOur hormones shape us at every stage of our lives, from the second we are conceived to the moment we breathe our last breath. They are essential to our immune system, sleep, digestion, hunger, stress levels, and so much more. When our hormone systems aren’t functioning well, it wreaks havoc on our health and our wellbeing—and yet most of us know very little about the far-reaching power of the human body’s crucial chemical messengers.\u003cbr\u003e \u003cbr\u003eProfessor Max Nieuwdorp, an international authority on hormones, sets out to change this. He explores the role our hormones play from our early years through to puberty, pregnancy, and old age, combining stories from his day-to-day life treating his patients with the amazing, cutting-edge new science of hormones. These discoveries are changing the way that we understand our bodies, from the decline in male hormones during andropause to the new science on how gut bacteria affects our hormone balance.\u003cbr\u003e \u003cbr\u003eThis eye-opening, myth-busting book shines a light on the incredible and under-explored role of hormones, which are essential not only to our health, but to our moods, our social interactions, and so much of what makes us who we are.","brand":"None","offers":[{"title":"Hardcover","offer_id":46168363925681,"sku":"9781668053522","price":36.99,"currency_code":"CAD","in_stock":true},{"title":"Kobo eBook","offer_id":46168363958449,"sku":"7e5de74b-1af2-31ad-bac2-3ebc6fe578a4","price":29.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0655\/8980\/5233\/files\/1_006c4db3-bc32-425a-a98e-d41f9df2ec7c.jpg?v=1763546107"},{"product_id":"life-in-the-age-of-insulin","title":"Life in the Age of Insulin: A Brief History","description":"\u003cp\u003e\u003ci\u003eLife in the Age of Insulin\u003c\/i\u003eoffers a straightforward and jargon-free narrative account of how insulin was discovered, what it does, why people still struggle to obtain it, and what the future might hold. It tells of the creative power that emerges when many people work towards a common goal, and of collective strength founded upon the limitations of individuals.\u003c\/p\u003e\u003cp\u003eIt envisages a future of competitive insulin pricing and revolutionary therapies, kindling hope for health equity.\u003c\/p\u003e\u003cp\u003eWith over 70 million insulin users world-wide, this book bridges the gap for patients and families. It will appeal to health professionals, to those intrigued by science, and to anyone who likes a good story.\u003c\/p\u003e\u003cp\u003e\u003ci\u003eLife in the Age of Insulin\u003c\/i\u003eis an empathetic and enlightening saga of science, society and human resilience.\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e\u003c\/p\u003e","brand":"None","offers":[{"title":"Hardcover","offer_id":46170775617713,"sku":"9783031471896","price":43.95,"currency_code":"CAD","in_stock":true},{"title":"Kobo eBook","offer_id":46170775650481,"sku":"6c089c18-c173-324d-9080-3a4dd5fd30b6","price":34.89,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0655\/8980\/5233\/files\/1_259d4716-52dc-4534-95c1-f84904176051.jpg?v=1763442026"},{"product_id":"control-of-metabolic-processes","title":"Control of Metabolic Processes","description":"THIS BOOK collects together papers given at a NATO Advanced Research Workshop held at Il Ciocco (Lucca), Italy, from the 9th to the 15th April, 1989. It sets out to present the current state of understanding of the principles governing the way fluxes and concentrations are maintained and controlled in metabolic systems. Although this is a topic that has held the interest of biochemists for many years, it is only quite recently that the methods of analysing the kinetics of multi-enzyme pathways developed over the past two decades have come to be widely discussed or applied experimentally. Many biochemists remain sceptical that the new methods offer a real advance (except in complexity) over the landmark discoveries of the 1950s and 1960s relating to inhibition of enzymes at branch-points by the end products of metabolic pathways, and the interpretation of allosteric effects and cooperativity. Even those who have become convinced that the classical ideas provide only the starting point for understanding metabolic control have been by no means unanimous in their assess­ ment of the direction in which one should advance. In this book we have tried to include all of the current points of view, including the view that the classical theories tell us all that we need to know. We have not seen it as our role as editors to paper over the cracks that exist and to pretend that we can speak to the world with one voice.","brand":"None","offers":[{"title":"Paperback","offer_id":46176901202097,"sku":"9781475798586","price":321.5,"currency_code":"CAD","in_stock":true},{"title":"Hardcover","offer_id":46176901234865,"sku":"9780306435829","price":285.95,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0655\/8980\/5233\/files\/1_35bee7eb-0d29-412f-992b-61dcab6f46ad.jpg?v=1764389444"},{"product_id":"care-of-older-people-with-diabetes","title":"Care of Older People with Diabetes: A Manual for Healthcare Practice","description":"\u003cp\u003e\u003cb\u003eA concise and accessible overview to the treatment of diabetes in older patients\u003c\/b\u003e \u003c\/p\u003e\u003cp\u003eCare of older people is rapidly becoming one of the most important components of the healthcare profession. An ageing population provides new challenges for the healthcare industry and drives new demand for healthcare professionals with dedicated elder care experience and training. Few aspects of care for older patients are more important than diabetes, a condition characterized by its unique challenges and clinical heterogeneity. \u003c\/p\u003e\u003cp\u003e\u003ci\u003eCare of Older People with Diabetes\u003c\/i\u003e offers a concise and readable introduction to the essentials of this vital clinical practice. Building on the knowledge contained within the successful \u003ci\u003eDiabetes in Old Age\u003c\/i\u003e textbook series, this book brings to bear the work of global experts in the field to provide a working reference for students and early career healthcare professionals alike. Anyone with an interest in caring for older patients with diabetes should find this a lucid and invaluable resource. \u003c\/p\u003e\u003cp\u003e\u003ci\u003eCare of Older People with Diabetes\u003c\/i\u003e readers will also find: \u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eOne to two clinical case questions per chapter with model answers\u003c\/li\u003e \u003cli\u003eClear and easy-to-follow division into Background, Key Facts, and Key Management aspects\u003c\/li\u003e \u003cli\u003eA minimum of 10 key references per chapter\u003c\/li\u003e\n\u003c\/ul\u003e \u003cp\u003e\u003ci\u003eCare of Older People with Diabetes\u003c\/i\u003e is ideal for medical and nursing students, early career doctors, senior nurses, and all other members of the healthcare team.\u003c\/p\u003e","brand":"None","offers":[{"title":"Paperback","offer_id":46177601290417,"sku":"9781394205035","price":191.95,"currency_code":"CAD","in_stock":true},{"title":"Kobo eBook","offer_id":46177601323185,"sku":"da921ab8-8763-352b-b0e9-bbb4eafe4de5","price":153.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0655\/8980\/5233\/files\/1_6ce241b6-63ab-4a07-8825-bfedd3b0224a.jpg?v=1763679160"},{"product_id":"a-case-based-guide-to-clinical-endocrinology","title":"A Case-Based Guide to Clinical Endocrinology","description":"\u003cp\u003eIn \u003cem\u003eA Case-Based Guide to Clinical Endocrinology\u003c\/em\u003e, \u003cem\u003eSecond Edition,\u003c\/em\u003e a renowned group of distinguished clinicians once again provides stimulating instruction and insights into a wide variety of endocrine topics, teaching readers modern management of the conditions described and offering targeted entry into the literature. Importantly, many of the important elements in the current curriculum for clinical endocrine training as recommended by the Association of Program Directors in Clinical Endocrinology, Diabetes and Metabolism are covered in this text. Thoroughly updated, this new edition not only covers new treatment approaches but also emphasizes the latest investigative advances in both imaging and molecular diagnostics. To reinforce learning and retention of knowledge, a question-based approach is used in many of the case studies. Students, residents, fellows, and practitioners will find this reference to be an efficient way to review their understanding and increase their skills and abilities in patient investigation and management. An invaluable contribution to the field, \u003cem\u003eA Case-Based Guide to Clinical Endocrinology\u003c\/em\u003e, \u003cem\u003eSecond Edition,\u003c\/em\u003e offers the same comprehensive volume of thought-provoking case-studies that made the first edition of significant importance to all clinicians who treat patients with endocrine disorders.\u003c\/p\u003e\r\n","brand":"None","offers":[{"title":"Kobo eBook","offer_id":46176588660913,"sku":"58a5cfef-7756-33b5-ac46-f6b6642dcf90","price":128.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0655\/8980\/5233\/files\/image_5ec8c57b-8230-46c5-999b-b800e4655e89.jpg?v=1763167480"},{"product_id":"hormones-and-nutrition-in-obesity-and-cachexia","title":"Hormones and Nutrition in Obesity and Cachexia","description":"\u003cp\u003eInternational experts are brought together in this book to give basic as well as clinical data on obesity and cachexia, and an integrated picture of the regulation of intermediary metabolism in both situations. The data provide evidence that tissue catabolism and anabolism are regulated by similar mechanisms, which again are the target of different hormonal and metabolic factors. This joint discussion of the similarities evident in both areas will greatly benefit future understanding and research in obesity and cachexia.\u003c\/p\u003e\r\n","brand":"None","offers":[{"title":"Kobo eBook","offer_id":46176362791089,"sku":"4394fd1f-b22f-3986-93a1-621ebfa7d4aa","price":154.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0655\/8980\/5233\/files\/image_1d3dbcd1-691a-4f53-af56-27be6b74e565.jpg?v=1763139581"},{"product_id":"reproductive-endocrinology","title":"Reproductive Endocrinology: A Molecular Approach","description":"\u003cp\u003eMolecular biology emerged from advances in biochemistry during the 1940s and 1950s, when the structure of the nucleic acids and proteins were elucidated. Beginning in the 1970s, with nucleic acid enzymology and the discovery of the restriction enzymes, the tools of molecular biology became widely available and applied in cell biology to study how genes are regulated. This new knowledge impacted endocrinology and reproductive biology since it was largely known that the secretion of the internal glands affected the phenotypes, and expression of genes. Modern reproductive biology encompasses every level of biological study from genomics to ecology, encompassing cell biology, biochemistry, endocrinology and general physiology. All of these disciplines require a basic knowledge, both as a tool and as an essential aid to a fundamental understanding of the principles of life in health and disease. Overall, molecular biology is central to scientific studies in all living matter, impacting disciplines such as medicine, related health sciences, veterinary, agriculture and environmental sciences. In this book, the basic biochemistry of nucleic acids and proteins are reviewed. Methodologies used to study signaling and gene regulation in the endocrine\/reproductive system are also discussed. Topics include mechanisms of hormone action and several endocrine disorders affecting the reproductive system. Professionals in the medical, veterinary and animal sciences fields will find exciting and stimulating material enhancing the breadth and quality of their research.\u003c\/p\u003e","brand":"None","offers":[{"title":"Paperback","offer_id":46177305166001,"sku":"9781489984838","price":155.95,"currency_code":"CAD","in_stock":true},{"title":"Kobo eBook","offer_id":46177305198769,"sku":"8ffd77ab-5d3a-3db0-98ab-14b1ac6559fa","price":128.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0655\/8980\/5233\/files\/1_073accc7-02ce-43c6-9be1-bcdfb880c003.jpg?v=1762856124"},{"product_id":"encyclopedia-of-endocrine-diseases","title":"Encyclopedia of Endocrine Diseases","description":"\u003cp\u003e\u003ci\u003eThe Encyclopedia of Endocrine Diseases, Third Edition, Five Volume Set\u003c\/i\u003eis an essential one-stop reference exploring physiological, clinical diagnostic and therapeutic aspects of a wide range of endocrine and endocrine-related metabolic diseases. This edition incorporates ground-breaking research that has occurred in the last 8 years particularly in molecular mechanisms such as mutations, epigenetics and signaling, environmental effects on homeostasis, and the pathogenesis of common endocrine diseases including endocrine malignancies, obesity, and diabetes.\u003cbr\u003e\u003cbr\u003eAmong the most complex constructs in the body, the endocrine system sends chemical signals to specific receptors in other parts of the body, eliciting intracellular signaling pathways as their biological effect. The endocrine system regulates numerous processes including metabolism, biological cycles, internal fluid volume, reproduction and growth to maintain body homeostasis. However, the ways in which endocrine functioning can go awry are numerous. Providing over 400 updated articles, this 5 volume edition of Encyclopedia of Endocrine Diseases explores the extensive spectrum of metabolic and endocrine disease, capturing new diagnosis techniques, treatment methods and understanding of endocrine pathogenesis.\u003cbr\u003e\u003cbr\u003eThis text, unique in its vast coverage and clear layout, is not only an indispensable resource for clinical professionals and researchers in endocrinology, but also accessible to advanced and undergraduate students.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cul\u003e\n\u003cli\u003eProvides concise descriptions of the physiology and pathology of endocrine and metabolic functions. These will help students, as well as interdisciplinary and industrial researchers, who wish to understand how their research relates to endocrine and metabolic function.\u003c\/li\u003e\n\u003cli\u003eIncorporates perspectives from experts working within the domains of biomedicine such as physiology, pharmacology, immunology, and genetics, and clinical sciences such as pediatrics, metabolism, gynecology, geriatrics, and neurology\u003c\/li\u003e\n\u003cli\u003eFeatures cross-referencing of related articles along with striking X-ray, histological and diagrammatic images\u003c\/li\u003e\n\u003cli\u003eArticles are written with the online user in mind They follow a clear and consistent template that enables the effective use of multimedia\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"None","offers":[{"title":"Hardcover","offer_id":46174935154865,"sku":"9780443138256","price":5624.5,"currency_code":"CAD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0655\/8980\/5233\/files\/1_ea443ab0-1da1-4b38-8254-323fd43ff61e.jpg?v=1762856120"},{"product_id":"endemic-cretinism","title":"Endemic Cretinism","description":"\u003cp\u003eResponding to a renewed interest in the growing problem of iodine deficiency worldwide, Drs. Charles Oxnard and Peter Obendorf, along with experienced translator and anatomist John Dennison, take a fresh look at the classic text, \u003ci\u003eDer endemische Kretinismus\u003c\/i\u003e, published in 1936 by Springer. Translated here for the first time into English, this landmark text will be a welcome resource for researchers confronting the problem of iodine deficiency. Oxnard and Obendorf point out that there is very little detailed knowledge or numerical data on cretinism available in the English-speaking world.  In addition, highly-renowned Professor Basil S. Hetzel, recently-retired World Health Organization Chairman of the International Council for Control of Iodine Deficiency Disorders, published in 2009 with Dr Chen Zu-pei on the resurgence of iodine deficiency in China.  Indeed, throughout the entire developing world there may be as many as two billion people at risk to iodine deficiency; perhaps three quarters of a billion have goiter, and ten million may be cretins.  Even in developed countries, iodine deficiency is re-emerging (as in New South Wales in 19% of children) with the result of significantly reduced numbers of gifted children (though this is not cretinism \u003ci\u003eper se\u003c\/i\u003e). Certain to be of significant interest to a wide range of researchers, health providers and professionals, including government health administrators, this English translation of \u003ci\u003eEndemic Cretinism\u003c\/i\u003e is a major contribution to the literature.\u003cbr\u003e\u003c\/p\u003e","brand":"None","offers":[{"title":"Paperback","offer_id":46175747932337,"sku":"9781489997821","price":155.95,"currency_code":"CAD","in_stock":true},{"title":"Hardcover","offer_id":46175747965105,"sku":"9781461402800","price":248.5,"currency_code":"CAD","in_stock":true},{"title":"Kobo eBook","offer_id":46175747997873,"sku":"a51b3249-73ec-33fc-b3ca-0c3b0d2528b6","price":128.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0655\/8980\/5233\/files\/1_30841b43-3a66-4b4c-851a-8bb4346517bd.jpg?v=1764396634"},{"product_id":"diseases-of-the-pituitary","title":"Diseases of the Pituitary: Diagnosis and Treatment","description":"Nineteen cutting-edge review articles by leading authorities provide a comprehensive overview of the normal function of the pituitary and of the diagnosis and treatment of pituitary disorders. Topics range from normal hypothalamic-pituitary interactions and the processes that disrupt them to new advances in pituitary imaging and appropriate surgical intervention in various pituitary disorders. Among the diseases discussed are congenital hypopituitarism, deficiency states, strategies for evaluating patients with hyperprolactinemia, Cushing's syndrome, acromegaly, and glycoprotein pituitary tumors.","brand":"None","offers":[{"title":"Paperback","offer_id":46181212782769,"sku":"9781461284383","price":175.5,"currency_code":"CAD","in_stock":true},{"title":"Hardcover","offer_id":46181212815537,"sku":"9780896033641","price":248.5,"currency_code":"CAD","in_stock":true},{"title":"Kobo eBook","offer_id":46181212848305,"sku":"8c2e3cfb-5984-3fb2-a9c0-d1a70e6e72f5","price":128.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0655\/8980\/5233\/files\/1_3461d19e-df48-4248-8ba6-ea9a12cad732.jpg?v=1762239232"},{"product_id":"principles-of-hormone-behavior-relations","title":"Principles Of Hormone\/behavior Relations","description":"\u003cp\u003e\u003ci\u003ePrinciples of Hormone\/Behavior Relations, Second Edition,\u003c\/i\u003eprovides an introduction to the underlying principles of endocrine regulation of behavior, a newly emerging area of research within neurobiology and endocrinology. It addresses the properties of hormone\/behavior relations, including the influence of family background, timing issues, neuroanatomical features, cellular mechanisms, and the importance of environmental context and evolution. This new edition incorporates critical advances in the field, also including increased coverage of hormonal influences on food intake, and on the cardiovascular system.\u003c\/p\u003e\u003cp\u003eThe addition of entirely new principles provides further coverage of epigenetics and appetite. Thoroughly revised and updated, this book is an ideal resource for neuroscientists and researchers engaging in this rapidly expanding field of study.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cul\u003e\n\u003cli\u003eProvides a unique structure where each chapter addresses a key principle that is illustrated by numerous basic experimental and clinical examples\u003c\/li\u003e\n\u003cli\u003eIncludes user-friendly features, such as boxed figures with extended captions and references, numerous clinical notes, and a comprehensive list of abbreviations\u003c\/li\u003e\n\u003cli\u003eContains numerous illustrations that highlight both the clinical and basic science information\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"None","offers":[{"title":"Paperback","offer_id":46179054944433,"sku":"9780128113714","price":133.5,"currency_code":"CAD","in_stock":false},{"title":"Hardcover","offer_id":46179054977201,"sku":"9780125531498","price":100.95,"currency_code":"CAD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0655\/8980\/5233\/files\/1_e6b778cd-fa6c-4c06-b089-cb48bf768495.jpg?v=1763109023"},{"product_id":"hormone-replacement-therapy","title":"Hormone Replacement Therapy","description":"A. Wayne Meikle and a distinguished panel of expert clinicians bring to bear their extensive knowledge and experience in managing adults and children undergoing hormone replacement therapy for the pituitary, parathyroid, thyroid, pancreas, adrenal glands, and gonads. Emphasizing proper patient management, the book provides to specialists and general practitioners alike time-tested, cutting-edge guidelines on the use, monitoring, and dosage of hormone therapeutics in the treatment of disorders of endocrine function, while giving an exhaustive analysis of each therapy. Comprehensive and eminently practical, Hormone Replacement Therapy captures the most recent advances in hormone replacement therapeutics and is certain to serve endocrinologists, gynecologists, pediatricians, urologists, internists, and family practitioners as today's standard reference for managing and monitoring their patients.\u003cbr\u003e","brand":"None","offers":[{"title":"Paperback","offer_id":46181221695665,"sku":"9781617370922","price":321.5,"currency_code":"CAD","in_stock":true},{"title":"Hardcover","offer_id":46181221728433,"sku":"9780896036017","price":321.5,"currency_code":"CAD","in_stock":false},{"title":"Kobo eBook","offer_id":46181221761201,"sku":"f2229d57-b056-3a24-8fbb-7f143fd23564","price":258.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0655\/8980\/5233\/files\/1_cabf030b-6fb3-40fb-99d2-de9b32d13960.jpg?v=1764384041"},{"product_id":"hormones-and-the-heart-in-health-and-disease","title":"Hormones and the Heart in Health and Disease","description":"The maintenance of arterial blood pressure and the distribution of blood flow to the various organs of the body depends on the control of the pumping action of the heart and of the resistance of the vascular beds in the individual organs in accordance with their metabolic needs. These controls are achieved through the integrated actions of circulat­ ing hormones, humoral factors that are synthesized and released in the heart and blood vessels, and the autonomic nervous system. The heart, however, is not only the target for the direct and indirect actions of a number of hormones and humoral factors, it is also an endocrine organ in the traditional sense, synthesizing and secreting into the circulation chemical factors that act at distant sites. In this treatise, Hormones and the Heart in Health and Disease, we interpret \"endocrinology\" broadly and consider traditional hormones as well as autocoids that are secreted by the heart or that act on it. In this overview, the relevant chapters are indicated in parentheses. The discovery of atrial natriuretic peptide (ANP; atrial natriuretic factor, ANF) in the 1980s indicated that the heart does indeed function as an endocrine organ in the classic sense. ANP (Chapter I) is synthesized in the heart and secreted into the circulation for actions on the kidney, where it is a potent natriuretic agent, and on the vasculature, where it causes vasodilation. ANP can also affect myocardial contractility.","brand":"None","offers":[{"title":"Paperback","offer_id":46181213536433,"sku":"9781475754209","price":160.95,"currency_code":"CAD","in_stock":true},{"title":"Hardcover","offer_id":46181213569201,"sku":"9780896037267","price":321.5,"currency_code":"CAD","in_stock":true},{"title":"Kobo eBook","offer_id":46181213601969,"sku":"7debd6e3-f177-39a5-a5dc-f6001c2e1a54","price":116.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0655\/8980\/5233\/files\/1_cb19f78f-3a00-476a-a75f-2f2363ad5e89.jpg?v=1764388234"},{"product_id":"introduction-to-psychoneuroimmunology","title":"Introduction to Psychoneuroimmunology","description":"\u003cp\u003eHealth is maintained by the coordinated operation of all the biological systems that make up the individual.\u003ci\u003eThe Introduction to Psychoneuroimmunology, Second Edition,\u003c\/i\u003epresents an overview of what has been discovered by scientists regarding how bodily systems respond to environmental challenges and intercommunicate to sustain health. The book touches on the main findings from the current literature without being overly technical and complex. The result is a comprehensive overview of psychoneuroimmunology, which avoids oversimplification, but does not overwhelm the reader.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cul\u003e\n\u003cli\u003eSingle authored for consistency of breadth and depth, with no redundancy of coverage between chapters\u003c\/li\u003e\n\u003cli\u003eCovers endocrine-immune modulation, neuro-immune modulation, and the enhancing or inhibiting processes of one or more systems on the others\u003c\/li\u003e\n\u003cli\u003eExpanded use of figures, tables, and text boxes\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"None","offers":[{"title":"Hardcover","offer_id":46179049144497,"sku":"9780123820495","price":133.5,"currency_code":"CAD","in_stock":true},{"title":"Kobo eBook","offer_id":46179049177265,"sku":"9d419529-0d02-37ad-b1a3-42f0d72beef7","price":63.19,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0655\/8980\/5233\/files\/1_8f438190-5a9b-4cf8-b717-8e4d0ab88ae8.jpg?v=1762337964"},{"product_id":"management-of-prader-willi-syndrome","title":"Management Of Prader-willi Syndrome","description":"\u003cp\u003eNow in a fully revised and updated fourth edition, this book remains the most comprehensive resource on Prader-Willi syndrome (PWS) available on the market. There have been significant changes in the diagnosis, clinical care and treatment of PWS since the previous edition was published in 2006, and more thorough information on understanding the cause and diagnosis of the condition, along with clinical presentation and findings with natural history data now available. \u003c\/p\u003e\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\u003cp\u003eThe book is divided into three thematic sections. Part One discusses the genetics, diagnosis, research and overview of PWS, including current laboratory testing. The medical physiology and treatment of PWS comprise Part Two, covering the GI system, obesity as well as the use of growth hormone. Part Three, the largest section, presents a wide-ranging, multidisciplinary management approach to PWS, attending to the many manifestations of the condition. Topics here include neurodevelopmental aspects, speech and language disorders, motor issues, psychological and behavioral management, educational and transitional considerations, vocational training and residential care, and advocacy for both school discipline and sexuality. Syndrome-specific growth charts, benefits eligibility information and additional resources are included in helpful appendices. \u003c\/p\u003e\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\u003cp\u003eTimely and well-crafted, this latest edition of\u003ci\u003eManagement of Prader-Willi Syndrome\u003c\/i\u003eremains the gold standard for clinicians and health care providers working with patients diagnosed with this rare obesity-related genetic disorder.\u003c\/p\u003e\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e","brand":"None","offers":[{"title":"Hardcover (2022)","offer_id":46179891544241,"sku":"9783030981709","price":248.5,"currency_code":"CAD","in_stock":false},{"title":"Hardcover (2025)","offer_id":46179891577009,"sku":"9780387253978","price":248.5,"currency_code":"CAD","in_stock":true},{"title":"Kobo eBook","offer_id":46179891609777,"sku":"65bc5e0e-5f1a-3550-b4f5-43c282064617","price":128.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0655\/8980\/5233\/files\/1_3446ce11-f9ae-4248-a3ba-f11f5445315f.jpg?v=1762422948"},{"product_id":"metabolic-effects-of-gonadal-hormones-and-contraceptive-steroids","title":"Metabolic Effects of Gonadal Hormones and Contraceptive Steroids","description":"The Center for Population Research of the National Institute of Child Health and Human Development began operations in August 1968 and is engaged in research dealing with health-related popula- tion problems. We organize and support projects for the develop- ment of new contraceptives and in the broad field of population research in the social sciences o The Center also supports a variety of projects dealing with the mechanism of action and medical effects of contraceptives now in use, particularly oral contraceptives and intrauterine devices. These studies were initiated several years ago at the specific direction of Congresso We were pleased, therefore, with the opportunity to help organize and support this important and timely conference on the \"Metabolic Effects of Gonadal Hormones and Contraceptive Steroids,\" the subject of which forms an integral part of the Center's research program. April, 1969 Philip Ao Corfman Director Center for Population Research National Institute of Child Health and Human Development v PREFACE Progress in science is often associated with either a \"sixth sense\" or an inevitable timeliness. Both factors, perhaps, led the members of the Endocrinology Study Section of the National Institutes of Health to propose, in 1966, that an expanded view of the effects of gonadal hormones, in general, and the contra- ceptive steroids, in particular. was needed. There had been ample evaluations of the clinical symptomatology, contraceptive efficacy, and effects on the reproductive system, but there was a dearth of information on their multiple systemic'metabolic effects.","brand":"None","offers":[{"title":"Paperback","offer_id":46179407691953,"sku":"9781468417845","price":71.5,"currency_code":"CAD","in_stock":true},{"title":"Kobo eBook","offer_id":46179407724721,"sku":"bb4b52ef-d56b-3b15-ae28-9e07e7960c12","price":64.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0655\/8980\/5233\/files\/1_3b47bea7-33d8-490c-b94c-dfc7bf8273e2.jpg?v=1764387555"},{"product_id":"office-based-infertility-practice","title":"Office-Based Infertility Practice","description":"The practice of clinical reproductive medicine has practice in the era of managed care and coordinat­ gradually moved from its initial 1980-90 hospital ing ancillary offsite medical personnel. base to its present (circa 2001) office site of oper­ The objective of this text is to assist in this ongo­ ation. With this transition have been improvements ing endeavor by presenting in a clear, concise man­ in efficiency of practice often in response to ner many of the topics relevant to contemporary increased pressure to provide the most patient sat­ office-based infertility practice. The initial half of isfaction. An added challenge of office-based prac­ this text addresses topics which focus upon general tice has been taking on many of the responsibili­ concepts of infertility evaluation and practice. The ties of what had been traditionally the hospital's latter half is a practical approach to the execution domain. Some of these new responsibilities have of specific office-based infertility procedures. We included the ordering of operative supplies and hope this book will assist all medical personnel who equipment, the establishment of quality control dedicate their clinical effort in achieving what is programs, construction and maintenance of special most coveted by our patients, the birth of a healthy laboratory spaces, redesigning efficient methods of newborn. DAVID B. SEIFER, M. D. UMDNJ-Robert Wood Johnson Medical School ROBERT L. COLLINS, M. D. The Reproductive Center, Youngstown, Ohio October 2001 vii Contents Preface . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . vii . . . . . . . . . . . . . . . . . Contributors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . xi . . . .. . . . . . . . . . . . . 1 Evaluation of the Female for Infertility . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 Bryan D.","brand":"None","offers":[{"title":"Paperback","offer_id":46179950592177,"sku":"9783642876929","price":80.5,"currency_code":"CAD","in_stock":true},{"title":"Hardcover","offer_id":46179950624945,"sku":"9780387983905","price":160.95,"currency_code":"CAD","in_stock":true},{"title":"Kobo eBook","offer_id":46179950657713,"sku":"a5743a5f-96f3-378f-b36d-07ceeb3ee595","price":116.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0655\/8980\/5233\/files\/1_d0b55c05-f6bd-4673-a9ac-32d9ed79075d.jpg?v=1762933269"},{"product_id":"art-and-the-human-blastocyst","title":"ART and the Human Blastocyst","description":"The field of human artificial reproductive technology (ART) is continually advancing and has witnessed significant changes since the inception of Louise Brown in 1978. Though Louise Brown herself was conceived after the trans­ fer of a blastocyst, there remain significant confusion and debate regarding the stage at which the human embryo conceived in the laboratory should be replaced in the mother. Developments in culture media formulations, leading to the introduction of sequential media, have brought the role of the blasto­ cyst in human ART back into the spotlight. It was due to this resurgence of interest in the niche of extended culture in human infertility treatment that the symposium on \"ART and the Human Blastocyst\" was held. of this meeting within this volume bring to the forefront The proceedings the main issues raised with the transfer of embryos at the blastocyst stage. It is evident from the chapters that follow that ART needs to be perceived as a continuum of procedures, each one dependent on the preceding one, and all equally as important as each other. That is to say, the development of a com­ petent embryo is ultimately dependent on the quality of the gametes from which it was derived. With regard to the oocyte, this then places the emphasis on the physician to use a stimulation protocol that both produces quality oocytes and does not impair endometrial function. Maintenance of gamete and embryo quality is the laboratory's role.","brand":"None","offers":[{"title":"Paperback","offer_id":46179945021617,"sku":"9781461265405","price":80.5,"currency_code":"CAD","in_stock":true},{"title":"Kobo eBook","offer_id":46179945054385,"sku":"b9eeae2c-0bdf-346d-a786-856d0fbdcca4","price":64.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0655\/8980\/5233\/files\/1_3f0474c0-9033-45af-bd24-0d0e3bc51645.jpg?v=1763136699"},{"product_id":"obesity","title":"Obesity: Evaluation And Treatment Essentials","description":"\u003cp\u003eObesity is considered a complex and multifactorial disease. Its treatment, therefore, must also be multimodal and tailored to meet the needs of each patient.\u003cstrong\u003eObesity: Evaluation and Treatment Essentials\u003c\/strong\u003e presents a wide spectrum of practical treatment protocols for obesity including exercise, pharmacology, behavior modification, and dietary factors, from the point of view of the practicing physician.\u003c\/p\u003e\u003cp\u003eThe book includes information about the new pharmacotherapy available for the treatment of obesity. It also includes a chapter on medical treatment of pediatric obesity that identifies the special needs of children and outlines approaches for managing the obese child. A chapter on binge eating disorder has been added and the information on pharmacology of bariatric medicine has been updated. The book addresses various dietary interventions such as low-calorie balanced diets, low-carbohydrate diets, and very-low-carbohydrate diets while also exploring the comorbidities of obesity such as hypertension, cardiovascular disease, and Type II diabetes.\u003c\/p\u003e\u003cp\u003eWritten by prominent members of the Obesity Medicine Association and a multidisciplinary team of clinicians and researchers, the book showcases successful treatment methods by including personal key points by clinicians in each chapter. This comprehensive resource is an invaluable, user-friendly tool for bariatric physicians and surgeons, endocrinologists, diabetologists, nutritionists, and dieticians, as well as all other professionals who currently treat obesity.\u003c\/p\u003e","brand":"None","offers":[{"title":"Hardcover","offer_id":46184933621937,"sku":"9781482262070","price":333.5,"currency_code":"CAD","in_stock":false},{"title":"Kobo eBook","offer_id":46184933654705,"sku":"ced1b012-f9e1-3081-b1fd-b4887b7d0bde","price":305.37,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0655\/8980\/5233\/files\/1_ca0ec0a0-201e-4910-a4e6-4d64fbcd4534.jpg?v=1762832465"},{"product_id":"obesity-before-birth","title":"Obesity Before Birth: Maternal and prenatal influences on the offspring","description":"This volume will explore the epidemiology and the basic mechanisms of each of these prenatal phenomena, in an attempt to explain the role of the prenatal environment in promoting postnatal weight gain. This information will contribute to resolving the nature-nurture controversy. This information provides guidance to clinical practitioners involved in both prenatal and postnatal care. This volume further stimulates research into underlying mechanisms and prevention and treatment of this phenomenon.","brand":"None","offers":[{"title":"Paperback","offer_id":46185038577841,"sku":"9781461426868","price":248.5,"currency_code":"CAD","in_stock":true},{"title":"Hardcover","offer_id":46185038610609,"sku":"9781441970336","price":321.5,"currency_code":"CAD","in_stock":true},{"title":"Kobo eBook","offer_id":46185038643377,"sku":"0c4f8042-0ac0-3b57-a489-b30af8855fd7","price":193.59,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0655\/8980\/5233\/files\/1_41771a30-2b03-4360-862b-ae4abf3104ad.jpg?v=1763136701"},{"product_id":"overweight-and-the-metabolic-syndrome","title":"Overweight And The Metabolic Syndrome: : From Bench To Bedside","description":"\u003cp\u003e\u003cem\u003eOverweight and the Metabolic Syndrome\u003c\/em\u003ewill provide an overview of topics related to obesity, including associated health risks, childhood obesity, genetics, evaluation, treatment, behavioral strategies, and successes and failures in preventing obesity.\u003c\/p\u003e\u003cp\u003eThe body composition that underlies obesity and the metabolic syndrome is key to understanding the problem. The mechanisms by which energy balance is maintained is key to how the problem goes wrong. The metabolic syndrome is in part a consequence of central fat storage, but includes more issues such as insulin resistance, low levels of inflammation, and endothelial dysfunction. This volume will cover evaluation guidelines, different approaches to treatment, including diet, exercise, behavior, drugs, and surgery to deal with the current world-wide obesity epidemic.\u003c\/p\u003e","brand":"None","offers":[{"title":"Paperback","offer_id":46185016590513,"sku":"9781441940735","price":248.5,"currency_code":"CAD","in_stock":true},{"title":"Hardcover","offer_id":46185016623281,"sku":"9780387321639","price":248.5,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0655\/8980\/5233\/files\/1_b0f2235b-75dd-43ee-be3e-f121dc3ddb8e.jpg?v=1764397816"},{"product_id":"oxidative-phosphorylation-in-health-and-disease","title":"Oxidative Phosphorylation in Health and Disease","description":"Mitochondrial diseases are often hard to diagnose. From the time they were first researched without animal models, patients of mitochondrial diseases were of equal interest to both clinical and basic scientists. With the new research done, this book includes updates on the normal structure, function, and molecular biology of the mitochondrial respiratory chain, information on traditional diagnostical methodologies, and an overview of the diagnostic promise of new technologies. The hypermetabolism of Luft disease, although only seen twice, is also studied. There are critical reviews of symptoms and signs associated with syndromes, as well as updates on the genetic defects of either the mitochondrial or the nuclear genome responsible for many disorders.","brand":"None","offers":[{"title":"Paperback","offer_id":46185009119409,"sku":"9781441934352","price":248.5,"currency_code":"CAD","in_stock":true},{"title":"Hardcover","offer_id":46185009152177,"sku":"9780306482328","price":248.5,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0655\/8980\/5233\/files\/1_68a03c24-3403-412a-bbdd-570b5477aa1a.jpg?v=1764400698"},{"product_id":"diagnosis-and-management-of-polycystic-ovary-syndrome","title":"Diagnosis and Management of Polycystic Ovary Syndrome","description":"\u003cp\u003eDiagnosis and Management of Polycystic Ovary Syndrome is a comprehensive clinical reference work for primary care physicians, internists, general endocrinologists, obstetricians, gynecologists and students. PCOS is a common but frequently misdiagnosed disease. Many symptoms can be alleviated by early intervention and effective management.\u003c\/p\u003e\u003cp\u003eProminent endocrinologists are gathered to detail current research and treatment in this metabolic disorder, affecting a growing population. The chapters are comprehensive, providing cutting edge knowledge on pathogenesis, manifestations, diagnosis and treatment of PCOS. Each chapter will be concise concluding with cogent practice points.\u003c\/p\u003e\u003cp\u003eThe variety of medical issues presenting in PCOS patients result in late referrals or in- appropriate advice. This title will be a tool in a further understanding of the metabolic and genetic basis of PCOS, while providing management strategies.\u003c\/p\u003e","brand":"None","offers":[{"title":"Paperback","offer_id":46185009578161,"sku":"9781441935236","price":202.95,"currency_code":"CAD","in_stock":true},{"title":"Kobo eBook","offer_id":46185009610929,"sku":"2680a42e-c810-35ba-8d16-8b157bcb028e","price":116.09,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0655\/8980\/5233\/files\/1_1021e224-d8be-4447-8bcc-cf12a05b24e9.jpg?v=1763136691"},{"product_id":"energy-metabolism-and-obesity","title":"Energy Metabolism and Obesity: Research and Clinical Applications","description":"\u003cem\u003eEnergy Metabolism and Obesity: Research and Clinical Applications\u003c\/em\u003eis a compilation of highly informative reviews written by undisputed leaders in the field.  These authors elucidate the most important aspects of genetic background, neuropeptide secretion and action, neuronal pathways, adipokines, gut hormones, and environmental influences (physical activity, pharmacologic agents, and surgical alteration of the gastrointestinal tract), as well as the complex interactions among them.  Understanding the physiology of energy storage and partitioning has become quite a daunting task.  This title enables researchers and clinicians to face the challenge of understanding this complex topic and applying the information to the practice of obesity prevention and treatment.  The excellent overviews in this book will undoubtedly provide readers with a better understanding of the multifaceted entity of obesity.","brand":"None","offers":[{"title":"Paperback","offer_id":46187120033969,"sku":"9781617377105","price":175.5,"currency_code":"CAD","in_stock":true},{"title":"Hardcover","offer_id":46187120066737,"sku":"9781588296719","price":248.5,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0655\/8980\/5233\/files\/1_275a3ae4-d6b1-4033-bfa9-bec8da82d263.jpg?v=1762238795"},{"product_id":"therapeutic-outcome-of-endocrine-disorders","title":"Therapeutic Outcome of Endocrine Disorders: Efficacy, Innovation and Quality of Life","description":"Changes in the allocation of healthcare resources have raised issues related to the efficacy and outcomes of medical therapy and how such factors may be measured. The questions associated with the quality of life and functional capability of patients with chronic health conditions have been of special interest. Endocrine disorders have the potential for disrupting the general health and well-being of affected individuals and their families; thus they warrant serious attention. This symposium was convened in November 1997 at Palm Beach Gardens, Florida, to bring together medical, behavioral, and social scientists. The meeting fostered the presentation and discussion of the most current clinical research on the effects of various therapies on a wide range of endocrine disorders from diabetes to adrenal insufficiency and growth hormone deficiency. The participants, all noted national and international experts in their fields, focused their attention on both the biomedical value and effectiveness of treatment, as well as on the impact such treatments have on psychological states such as mood and cognition. Many presentations specifically emphasized the quality of life (QOL) indicators that now regu­ larly appear in many research protocols and reports. The pioneering work of two clinical researchers was a major highlight of the meeting and an Award of Recognition was presented to Robert Blizzard, M. D. , and John Money, Ph. D. , for their innovative and insightful work in pediatric endocrinology and psychosexual development.","brand":"None","offers":[{"title":"Paperback","offer_id":46186263118001,"sku":"9781461270522","price":145.95,"currency_code":"CAD","in_stock":true},{"title":"Kobo eBook","offer_id":46186263150769,"sku":"8e63e68e-6ba4-326e-81c5-7f570e678f48","price":109.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0655\/8980\/5233\/files\/1_38163f34-074f-4303-9dd8-55e957d6865e.jpg?v=1762813437"},{"product_id":"amenorrhea","title":"Amenorrhea: A Case-Based, Clinical Guide","description":"Amenorrhea: A Case-Based Clinical Guide is a comprehensive review of the current knowledge regarding normal female reproductive physiology. Replete with interesting case vignettes and providing diagnostic algorithms and therapeutic strategies for amenorrhea, Amenorrhea: A Case-Based Clinical Guide is divided into three sections. The first section is composed of two chapters that provide a thorough review of basic science and clinical knowledge about the organ systems responsible for normal physiology of the menstrual cycle. The second section includes discussion about menstrual cycle disruption as it relates to hypothalamic-pituitary dysfunction, surgical and natural menopause, genetic defects, premature ovarian failure\/insufficiency and the effects of caloric excess and restriction. The third section offers an update on the physiological effects of prolonged amenorrhea induced surgically or by hypothalamic dysfunction and also includes an original chapter that focuses solely on the impact of race and ethnicity on the prevalence and diagnosis of amenorrhea. Amenorrhea: A Case-Based Clinical Guide brings together chapters from renowned experts who offer state-of-the-art, clinically useful information in a case-based, reader-friendly fashion. This title will be a welcome addition to the bookshelves of all clinicians who practice in women's health settings.","brand":"None","offers":[{"title":"Paperback","offer_id":46187122098353,"sku":"9781617797057","price":250.22,"currency_code":"CAD","in_stock":true},{"title":"Hardcover","offer_id":46187122131121,"sku":"9781603278638","price":348.95,"currency_code":"CAD","in_stock":true},{"title":"Kobo eBook","offer_id":46187122163889,"sku":"f248dcb2-c4dc-367f-be9b-d31acadbd4d1","price":258.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0655\/8980\/5233\/files\/1_b415f50f-f657-4b32-8ad3-af074cd97ffb.jpg?v=1762239231"},{"product_id":"the-diabetic-kidney","title":"The Diabetic Kidney","description":"A comprehensive and authoritative survey of recent findings, ideas, and hypotheses about the causes and treatment of diabetic nephropathy. The authors cover both the basic pathogenic mechanisms of the disease, as well as many of its clinical aspects of identification, management, and new therapeutic approaches. Highlights include an entire section devoted to novel approaches to studying diabetic nephropathy with the most advanced molecular techniques, and complete descriptions of the most up-to-date views on the diagnosis and treatment of the disease. The Diabetic Kidney offers both researchers and practicing clinicians a clear understanding of the of the progress that has been made regarding the pathogenesis of diabetic nephropathy and of the therapeutic interventions needed to prevent its development or treat it.","brand":"None","offers":[{"title":"Paperback","offer_id":46186952360113,"sku":"9781617376788","price":437.95,"currency_code":"CAD","in_stock":true},{"title":"Hardcover","offer_id":46186952392881,"sku":"9781588296245","price":321.5,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0655\/8980\/5233\/files\/1_8b2ededd-071e-473d-9fd0-a21ff589d8dc.jpg?v=1764383979"},{"product_id":"insulin-resistance","title":"Insulin Resistance: The Metabolic Syndrome X","description":"Gerald Reaven, the discoverer of Syndrome X, and a panel of world-class investigators thoughtfully summarize our current understanding of how insulin resistance and its compensating hyperinsulinemia play a major role in the pathogenesis and clinical course of high blood pressure and cardiovascular disease-the so-called diseases of Western civilization. These distinguished authorities detail, for the first time, the pathophysiological consequences and the clinical syndromes, excluding Type 2 diabetes, related to insulin resistance. They also examine the genetic and lifestyle factors that contribute to the wide differences in insulin action that exist in the population at large. Timely and authoritative, Insulin Resistance: The Metabolic Syndrome X illuminates the full importance of insulin resistance as a major cause of hypertension, heart disease, and polycystic ovary syndrome.\u003cbr\u003e","brand":"None","offers":[{"title":"Paperback","offer_id":46187115970737,"sku":"9781617370861","price":188.5,"currency_code":"CAD","in_stock":true},{"title":"Hardcover","offer_id":46187116003505,"sku":"9780896035881","price":261.5,"currency_code":"CAD","in_stock":false},{"title":"Kobo eBook","offer_id":46187116036273,"sku":"3eb4cb5e-25d6-3651-ba64-ae05a551cba2","price":141.89,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0655\/8980\/5233\/files\/1_6b2f36b5-2e9e-424f-a07b-8b14316b05af.jpg?v=1763137643"},{"product_id":"diabetes-and-c-peptide","title":"Diabetes And C-peptide: Scientific And Clinical Aspects","description":"\u003cp\u003eIn\u003ci\u003eDiabetes \u0026amp; C-Peptide: Scientific and Clinical Aspects\u003c\/i\u003e, a renowned group of leading researchers and physicians offers a comprehensive overview of the role of C-Peptide in type 1 diabetes. The book is organized in five sections. An Introductory section provides the background and key features of C-peptide's physiological function and how its deficiency contributes to complications. The second section describes up-to-date information on the biochemical and molecular actions of C-peptide, including membrane binding, interactions with insulin as well as the interaction between C-peptide and zinc and effects on microvascular vasoreactivity. The third section summarizes in vivo animal studies of the type 1 diabetic complications. The fourth section reviews the clinical efforts of C-peptide on inflammation, cardiovascular complication, neuropathy and nephropathy. Finally, in the Conclusions section, a summary of the present state of C-peptide, outstanding questions, and the likely direction of the field are offered. Developed by the foremost investigators in the rapidly moving field of C-peptide research,\u003ci\u003eDiabetes \u0026amp; C-Peptide: Scientific and Clinical Aspects\u003c\/i\u003eis an important contribution to the literature for all researchers and physicians concerned about type 1 diabetes.\u003c\/p\u003e","brand":"None","offers":[{"title":"Paperback","offer_id":46187127242929,"sku":"9781493959570","price":175.5,"currency_code":"CAD","in_stock":true},{"title":"Hardcover","offer_id":46187127275697,"sku":"9781617793905","price":248.5,"currency_code":"CAD","in_stock":true},{"title":"Kobo eBook","offer_id":46187127308465,"sku":"f6007ebd-de33-3649-8b37-4372df6af1eb","price":128.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0655\/8980\/5233\/files\/1_adf12d0a-b504-42a8-b0fc-25d9c238d018.jpg?v=1762813470"},{"product_id":"endocrinology-of-the-lung","title":"Endocrinology Of The Lung: Development And Surfactant Synthesis","description":"Carole Mendelson has assembled a panel of leading investigators to critically review the various classes of endocrine, paracrine, and neuroendocrine factors that play a role in the regulation of lung development and surfactant production. Special attention is accorded the actions of glucocorticoids in lung development and the synthesis of surfactant glycerophospholipids and proteins. Also extensively treated are the roles of cell-cell interactions and the elaboration of various growth factors and bioactive peptides in pulmonary cell differentiation, gene expression, and pathophysiology. State-of-the-art and comprehensive, Endocrinology of the Lung constitutes a powerful new standard guide that illuminates the complex endocrinology of the lung for all those actively investigating hormone action in pulmonary biology and medicine today.","brand":"None","offers":[{"title":"Paperback","offer_id":46186422599857,"sku":"9781468496086","price":175.5,"currency_code":"CAD","in_stock":true},{"title":"Kobo eBook","offer_id":46186422632625,"sku":"49b7ce2c-9ef2-30ee-98f0-19712732ccfb","price":128.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0655\/8980\/5233\/files\/1_470e98ab-eae6-4ef8-84c1-3805e4228323.jpg?v=1763191778"},{"product_id":"menopause","title":"Menopause: Endocrinology and Management","description":"Leading researchers and experienced clinicians join forces not only to illuminate today's understanding of the endocrinology of menopause, but also to provide a sound basis for its successful management. These seasoned experts review in detail the cardiovascular, bone, brain, and genitourinary changes that accompany menopause and spell out the risks, benefits, and alternatives of conventional hormone replacement therapy. Selective estrogen receptor modulators (SERMs), androgen replacement, calcium supplementation, and the role of phytoestrogens are also fully reviewed. Menopause: Endocrinology and Management offers practicing physicians a comprehensive understanding of the menopause process, as well as an evidence-based approach to optimizing treatment strategies for the challenging medical problems accompanying this important period in women's lives.","brand":"None","offers":[{"title":"Paperback","offer_id":46187114430641,"sku":"9781617371295","price":175.5,"currency_code":"CAD","in_stock":true},{"title":"Hardcover","offer_id":46187114463409,"sku":"9780896036772","price":248.5,"currency_code":"CAD","in_stock":false},{"title":"Kobo eBook","offer_id":46187114496177,"sku":"9abf4203-8183-33cf-b7c2-575cf4354569","price":128.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0655\/8980\/5233\/files\/1_a4c9b532-8179-430b-a887-20395a989626.jpg?v=1762239243"},{"product_id":"endocrine-emergencies","title":"Endocrine Emergencies: Recognition and Treatment","description":"\u003cp\u003eDeveloped by renowned experts, this comprehensive and easy to read title offers a state-of-the-art description of the management of endocrine, diabetic, and metabolic emergencies and brings the field fully up to date, setting a high standard for diagnosis and treatment in each category. All chapters begin with a summary that presents, in concentrated form, what the physician needs to know to begin the evaluation and emergency treatment of the known endocrine emergencies. This is followed by an extended discussion of the pathophysiology that can be read after initial treatment has begun. Covering such areas as hypoglycemia, acute adrenal insufficiency, ovarian hyperstimulation syndrome, thyroid storm, and pituitary apoplexy, just to name several,\u003ci\u003eEndocrine Emergencies: Recognition and Treatment\u003c\/i\u003eis an invaluable, practical resource that will be of great interest to endocrinologists, internal medicine and emergency room physicians, fellows and residents.\u003c\/p\u003e","brand":"None","offers":[{"title":"Paperback (2022 A)","offer_id":46186646339761,"sku":"9781493924189","price":145.95,"currency_code":"CAD","in_stock":true},{"title":"Paperback (2022 B)","offer_id":46186646372529,"sku":"9783030674571","price":160.95,"currency_code":"CAD","in_stock":true},{"title":"Hardcover","offer_id":46186646405297,"sku":"9783030674540","price":233.95,"currency_code":"CAD","in_stock":false},{"title":"Kobo eBook (2021)","offer_id":46186646438065,"sku":"c63325cc-2732-3a72-8da4-aaad10336d90","price":116.09,"currency_code":"CAD","in_stock":true},{"title":"Kobo eBook (2015)","offer_id":46186646470833,"sku":"40d7b01e-b61a-3eb2-8c15-fe2d31becbc6","price":167.79,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0655\/8980\/5233\/files\/1_b55bc2ac-35a4-4b7b-bf94-cf899dfe510f.jpg?v=1763137177"},{"product_id":"neurosteroids","title":"Neurosteroids: A New Regulatory Function in the Nervous System","description":"Etienne-Emile Baulieu, the discoverer of neurosteroids, and a panel of distinguished scientists and clinical researchers exhaustively and critically review all facets of neurosteroids involved in behavior, stress, memory, depression, anxiety, aging of the brain, and neurodegenerative diseases. These contributors illuminate the role of neurosteroids in brain development and plasticity and detail their neuromodulatory influence on GABAA, ionotropic glutamate receptors, acetylcholine receptors, sigma receptors, and calcium channels. Clearly pointing the way toward novel pharmaceutical agents that may be of significant therapeutic value, particularly with regard to aging mental functions, Neurosteroids: A New Regulatory Function in the Nervous System offers neurobiologists, psychiatrists, neurosurgeons, pharmacologists, and geriatricians the first comprehensive, state-of-the-art review of these important bioactive molecules.","brand":"None","offers":[{"title":"Paperback","offer_id":46187116232881,"sku":"9781617370687","price":321.5,"currency_code":"CAD","in_stock":true},{"title":"Kobo eBook","offer_id":46187116265649,"sku":"10ee6cff-36f6-3742-9247-1ddb5db736f2","price":258.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0655\/8980\/5233\/files\/1_ac564ee4-0bd6-4391-81f0-896d81ad5f10.jpg?v=1762239230"},{"product_id":"endocrinology-of-physical-activity-and-sport","title":"Endocrinology Of Physical Activity And Sport","description":"\u003cp\u003eNow in its fully revised and expanded third edition, this comprehensive text represents a compilation of the critical endocrinology topics in the areas of sports medicine, kinesiology and exercise science, written by leading experts in the field.\u003cbr\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e As in previous editions, the focus here is on the critical issues involved in understanding human endocrinology and hormonal workings with regards to physical activity, exercise and sport and how such workings impact the full range of medical conditions, overall health and physiological adaptation. Chapters included discuss the effect of exercise on the HPA axis, the GH-IGF-1 axis, thyroid function, diabetes, and the male and female reproductive systems, among other topics. Additional chapters present the current evidence on circadian endocrine physiology, exercise in older adults, exercise and hormone regulation in weight control, and the effects of overtraining in sports. Chapters brand new to this edition present the role of hormones in muscle hypertrophy, the effect of exercise on hormones in metabolic syndrome patients, how exercise impacts appetite-regulating hormones in clinical populations, and the relative energy deficiency in sport (RED-S) condition.\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cbr\u003e","brand":"None","offers":[{"title":"Paperback (2021 B)","offer_id":46187206148273,"sku":"9783030333782","price":189.95,"currency_code":"CAD","in_stock":false},{"title":"Paperback (2021 A)","offer_id":46187206181041,"sku":"9781493956340","price":262.95,"currency_code":"CAD","in_stock":true},{"title":"Hardcover","offer_id":46187206213809,"sku":"9783030333751","price":291.95,"currency_code":"CAD","in_stock":false},{"title":"Kobo eBook","offer_id":46187206246577,"sku":"c2c0fb3f-062b-321f-be4e-1d427210666b","price":141.89,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0655\/8980\/5233\/files\/1_99e3b555-8783-438b-af3d-9a44a3d9209a.jpg?v=1762239676"},{"product_id":"endocrinology-and-diabetes-1","title":"Endocrinology and Diabetes: Case Studies, Questions and Commentaries","description":"This book provides case studies accompanied by questions and commentaries for the specialist registrar in diabetes and endocrinology, to assist with problem-based learning during their training. The case studies range from the everyday to the rare and complicated, presenting a strong foundation for the specialist trainee to prepare them for their qualifying exams and, more importantly, for their future clinical consultations.","brand":"None","offers":[{"title":"Hardcover","offer_id":46186203971761,"sku":"9781447127888","price":175.5,"currency_code":"CAD","in_stock":true},{"title":"Kobo eBook","offer_id":46186204004529,"sku":"db360b9c-5f67-3631-8bbd-4ae3deb15ad9","price":109.69,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0655\/8980\/5233\/files\/1_90d3ef18-81ef-484c-9f7e-f3007334eef6.jpg?v=1762856945"},{"product_id":"diabetes-and-the-brain","title":"Diabetes and the Brain","description":"\u003cp\u003eDiabetes, particularly type 2, has become increasingly more common around the world. Consequently, the effect of diabetes on the brain has achieved enormous public health importance. A surge in pre-clinical and clinical research on topics ranging from management of hyperglycemia in acute stroke to disturbances in insulin signaling in Alzheimer's disease has led to substantial progress in the field. Written by a panel of international experts,\u003cem\u003eDiabetes and the Brain\u003c\/em\u003eprovides in depth reviews on the cerebral complications of diabetes, and offers introductory chapters on current insights on the pathophysiology and clinical management of diabetes, as well as neuropsychological assessment and dementia. This relevant and easily accessible book explains the cerebral complications of diabetes, with an update on diabetes for neurologists, psychiatrists, and mental health providers and researchers in general,and on stroke and dementia for those involved in research and clinical practice in diabetes.\u003c\/p\u003e","brand":"None","offers":[{"title":"Paperback","offer_id":46187121803441,"sku":"9781617796456","price":364.95,"currency_code":"CAD","in_stock":true},{"title":"Hardcover","offer_id":46187121836209,"sku":"9781603278492","price":321.5,"currency_code":"CAD","in_stock":true},{"title":"Kobo eBook","offer_id":46187121868977,"sku":"40315788-f580-3630-87a9-ba6195dbb578","price":258.09,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0655\/8980\/5233\/files\/1_2d3ad52b-8f3b-44ba-8326-49e68f59968e.jpg?v=1762857847"},{"product_id":"insulin-resistance-and-polycystic-ovarian-syndrome","title":"Insulin Resistance and Polycystic Ovarian Syndrome: Pathogenesis, Evaluation, and Treatment","description":"\u003cp\u003eDespite dizzyingly fast-paced advances over the past two decades, even the definition of Polycystic Ovarian Syndrome (PCOS) remains in dispute.\u003cem\u003eInsulin Resistance and Polycystic Ovarian Syndrome: Pathogenesis, Evaluation, and Treatment\u003c\/em\u003ehighlights the recent transition of PCOS from an infertility disorder with a diagnosis based on ovarian tissue histology to a more complex clinical entity, a metabolic disorder in which insulin resistance plays a central role.  With an expert panel of authors, each chapter provides an up-to-date and balanced overview of PCOS, paying special attention to the central role of insulin resistance in the syndrome's pathogenesis and in the management of its reproductive and metabolic abnormalities.\u003c\/p\u003e\u003cp\u003eComprehensive and thought-provoking,\u003cem\u003eInsulin Resistance and Polycystic Ovarian Syndrome: Pathogenesis, Evaluation, and Treatment\u003c\/em\u003eis an invaluable resource for endocrinologists, gynecologists, and internists eager to learn more about this controversial and challenging disease.\u003c\/p\u003e","brand":"None","offers":[{"title":"Paperback","offer_id":46187120427185,"sku":"9781617377631","price":364.95,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0655\/8980\/5233\/files\/1_a6f351a6-c329-434e-b1d9-03b2fc027534.jpg?v=1764386493"},{"product_id":"type-2-diabetes-mellitus","title":"Type 2 Diabetes Mellitus: : An Evidence-based Approach To Practical Management","description":"\u003cp\u003eAs the global epidemic of diabetes continues to expand, the prevalence of type 2 diabetes is predicted to double in the next 20 years. Type 2 Diabetes Mellitus: An Evidence-Based Approach to Practical Management addresses this problem by expertly synthesizing the currently available evidence regarding specific issues in diabetes care. Written by an interdisciplinary team of scientists and medical professionals and comprising a wealth of information in a single resource, the book integrates the best evidence for the full range of clinical issues surrounding the evaluation and treatment of type 2 diabetes, including comorbid conditions such as hypertension, hyperlipidemia, and vascular disease. To quantify the strength of evidence supporting current practices, each chapter highlights related conditions, including fatty liver disease, pregnancy, and polycystic ovarian syndrome, and also addresses barriers to treatment, including stress, depression, and patient motivation.\u003c\/p\u003e","brand":"None","offers":[{"title":"Paperback","offer_id":46186956783793,"sku":"9781617377839","price":364.95,"currency_code":"CAD","in_stock":true},{"title":"Hardcover","offer_id":46186956816561,"sku":"9781588297945","price":321.5,"currency_code":"CAD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0655\/8980\/5233\/files\/1_08a43b80-3d9b-4503-8fb2-758b7c8eb27b.jpg?v=1764386493"},{"product_id":"contemporary-treatment-of-erectile-dysfunction","title":"Contemporary Treatment Of Erectile Dysfunction: A Clinical Guide","description":"\u003cp\u003e\u003c\/p\u003e\u003cp\u003eNow in a revised and expanded second edition, this comprehensive clinical guide\u003ci\u003e \u003c\/i\u003eremains a state-of-the-art synthesis of the literature, covering all aspects of treating erectile dysfunction (ED) and other related male sexual dysfunctions. Cardiovascular, hormonal, psychological and lifestyle factors are each considered in diagnosis and treatment, which includes pharmacological, surgical and prosthetic management strategies. The effects of prostate cancer and its treatment are also discussed, as are Peyronie's disease, priapism and ejaculatory disorders. New chapters in this edition discuss the profound effects of lifestyle change on sexual function, alternative and internet drugs that affect sexual function, endovascular approaches to ED, penile length considerations, the effect of radiation on erectile function, and optimizing ED research. Presenting a better understanding of what causes erectile dysfunction and the effective medications and non-medicationtreatments used to treat the condition, this invaluable title offers all physicians, residents, and fellows - and even medical students and other health professionals such as nurse practitioners and physician assistants - an essential reference for enhancing diagnosis and treatment of this common and debilitating disorder.\u003c\/p\u003e","brand":"None","offers":[{"title":"Paperback (2018)","offer_id":46187007738033,"sku":"9783319810713","price":145.95,"currency_code":"CAD","in_stock":false},{"title":"Paperback (2024)","offer_id":46187007770801,"sku":"9781617795534","price":160.95,"currency_code":"CAD","in_stock":true},{"title":"Hardcover (2016 B)","offer_id":46187007803569,"sku":"9783319315850","price":204.5,"currency_code":"CAD","in_stock":true},{"title":"Hardcover (2016 A)","offer_id":46187007836337,"sku":"9781603275354","price":398.95,"currency_code":"CAD","in_stock":false},{"title":"Kobo eBook (2010)","offer_id":46187007869105,"sku":"cf5b8519-3eeb-3b3c-91b9-7b44d6299c81","price":116.09,"currency_code":"CAD","in_stock":true},{"title":"Kobo eBook (2016)","offer_id":46187007901873,"sku":"90db6205-1100-3a73-961a-8c3d131e8ce5","price":116.09,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0655\/8980\/5233\/files\/1_ac1bcae6-c582-49bc-a0d7-311267044c6b.jpg?v=1763139577"},{"product_id":"transgenics-in-endocrinology","title":"Transgenics in Endocrinology","description":"A panel of expert clinical and basic investigators summarize the state-of-the-art in the use of transgenic technology in a broad range of endocrinological applications. Up-to-date and comprehensive, Transgenics in Endocrinology reviews the most recent developments in the analysis of endocrine physiology and its pathologies through mouse models, and provides a host of creative approaches to understand better the complex processes that are characteristic of hormonal systems.","brand":"None","offers":[{"title":"Paperback","offer_id":46186421158065,"sku":"9781468496406","price":175.5,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0655\/8980\/5233\/files\/1_72e59a12-9447-4fce-a55c-8c6b6bc28b48.jpg?v=1762238807"},{"product_id":"graves-disease","title":"Graves' Disease: A Comprehensive Guide For Clinicians","description":"\u003cp\u003eThis indispensable volume is designed to facilitate the best possible physician-patient discussion on Graves' disease by providing the most up-to-date evidence-based information in a clinically useful and patient-centric manner. Comprehensive and covering such topics as Professionalism and the Art of Patient-centric Thyroidology, the Immunopathogenesis of Graves' Disease, and the Diagnosis and Management of Thyroid Storm, the book addresses all the important refinements in the treatment of Graves' disease in recent years. These include new indications and contraindications for antithyroid drugs, improved approaches to radioactive iodine therapy, the development of novel surgical techniques, and a better understanding of the combined use of these modalities, among other developments. Also addressed are the advances in the treatment of GO, including the use of disease activity and severity assessments to inform management decisions and the completion of the first randomized controlled therapeutic trials. Developed by a renowned group of internationally respected authorities,\u003ci\u003eGraves' Disease: A Comprehensive Guide for Clinicians\u003c\/i\u003eis a significant new reference that will be of great interest to all clinicians who treat this debilitating condition.\u003c\/p\u003e","brand":"None","offers":[{"title":"Paperback","offer_id":46186651943089,"sku":"9781493947355","price":189.95,"currency_code":"CAD","in_stock":false},{"title":"Hardcover","offer_id":46186651975857,"sku":"9781493925339","price":159.5,"currency_code":"CAD","in_stock":false},{"title":"Kobo eBook","offer_id":46186652008625,"sku":"233242b7-262a-32f0-a911-44e325df8678","price":116.09,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0655\/8980\/5233\/files\/1_e4c16fd4-5c75-404e-b9e8-195fedb15d7a.jpg?v=1762833078"},{"product_id":"research-in-congenital-hypothyroidism","title":"Research in Congenital Hypothyroidism","description":"Systematic screening for congenital hypothyroidism in the newborn was introduced some 15 years ago. The main objective was the prevention of mental retardation due to thyroid hormone deficiency during the early months of life. During the past decade screening programs have become routine throughout most of the industrialized world and many questions relating to implementation, organization and quality control of such programs have been largely resolved. Preliminary IQ and neurological data have indicated that screening and early treatment do, in fact, prevent mental retardation. However, a number of scientific questions related to congenital hypothyroidism remain unanswered and extensive research activities are ongoing in the field. The objective of the organizers of the Brussels workshop was to focus almost exclusively on these current research aspects of the screening programs. This workshop is the third international conference specifically devoted to neonatal thyroid screening. The first was held in La Malbaie in Quebec in the fall of 1979. That meeting was well organized and highly productive. Its proceedings constitute a bible in the field. After the Quebec meeting, we witnessed major and rapid advances in our understanding of neonatal thyroid physiology as well as screening methodology, organiza- tion, data management, the significance of an approach to false negative and false positive results, patient follow-up, and assessment of follow-up and treatment, and the psychoneurological evaluation of affected infants. Some of these aspects were further developed during a second highly pro- ductive international conference organized in Tokyo in 1982.","brand":"None","offers":[{"title":"Paperback","offer_id":46186419486897,"sku":"9781468475821","price":142.95,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0655\/8980\/5233\/files\/1_5f37cf8c-a761-4ea9-ae54-1333e3e0ff7d.jpg?v=1764395975"},{"product_id":"motivational-interviewing-in-diabetes-care","title":"Motivational Interviewing in Diabetes Care","description":"People with diabetes often struggle to make healthy choices and stay on top of managing their illness. Filling a vital need, this is the first book to focus on the use of motivational interviewing (MI) in diabetes care. The uniquely qualified authors--physician Marc P. Steinberg has devoted much of his career to diabetes care, and renowned clinical psychologist William R. Miller is the codeveloper of MI--present proven counseling techniques that can make any conversation with a patient more efficacious and motivating. Numerous sample dialogues illustrate specific ways to elicit patients' strengths and help them overcome barriers to change in such areas as eating habits, physical activity, medication use, insulin treatment, substance abuse, psychological issues, and more.\u003cbr\u003e\u003cbr\u003eThis book is in the Applications of Motivational Interviewing series, edited by Stephen Rollnick, William R. Miller, and Theresa B. Moyers.\u003cbr\u003e\u003cbr\u003eWinner (First Place)--\u003ci\u003eAmerican Journal of Nursing\u003c\/i\u003eBook of the Year Award, Adult Primary Care Category","brand":"None","offers":[{"title":"Paperback","offer_id":46186364043441,"sku":"9781462521630","price":55.5,"currency_code":"CAD","in_stock":true},{"title":"Hardcover","offer_id":46186364076209,"sku":"9781462521555","price":84.33,"currency_code":"CAD","in_stock":true},{"title":"Kobo eBook","offer_id":46186364108977,"sku":"cf6b0ea0-b741-3996-84e1-a2803ed5617a","price":39.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0655\/8980\/5233\/files\/1_54c492bd-c4d1-4699-9cbe-556060fc024f.jpg?v=1762876449"},{"product_id":"diabetes-and-peripheral-vascular-disease","title":"Diabetes And Peripheral Vascular Disease: Diagnosis And Management","description":"\u003cp\u003eIn\u003ci\u003eDiabetes and Peripheral Vascular Disease\u003c\/i\u003e, a panel of distinguished leaders in the field of medicine, podiatry, and vascular and endovascular therapy assimilate the latest literature on these issues and others for an in-depth review of the management of peripheral vascular disease. Providing an overview of the management of diabetes and diabetic foot changes as well as providing a view of cutting-edge and emerging topics in optimization of arterial status, this important title addresses pathophysiology, anatomy, diagnosis and management of diabetic peripheral vascular disease, emphasizing a multi-disciplinary approach. The first chapter of the book provides an overview of this complex disease process and discusses the teamwork required for optimal management. The chapters continue with the basic pathophysiology of diabetic atherosclerosis and a contemporary review of the management of diabetes. The genesis of diabetic foot ulceration and prevention and management strategies is covered, as is the effects of neuropathy and microvascular changes in the diabetic foot. In addition,\u003ci\u003eDiabetes and Peripheral Vascular Disease\u003c\/i\u003ecovers the microbiology of diabetic foot infections, the role of endovascular interventions and vascular surgery as well as the management of the complications of these procedures, the process of amputation for those patients who have progressed beyond a limb salvage situation, and the effects of diabetes on the cerebrovascular system as well as its implications in patients with aortoiliac disease. An invaluable addition to the literature on diabetes and peripheral vascular disease, the book will be of great interest internists, family practitioners, surgeons, podiatrists, wound care specialists, and vascular specialists. Students, residents, and fellows in surgical and medical specialties should also find this book of significant value and interest.\u003c\/p\u003e","brand":"None","offers":[{"title":"Paperback","offer_id":46187205066929,"sku":"9781493963317","price":189.95,"currency_code":"CAD","in_stock":true},{"title":"Hardcover","offer_id":46187205099697,"sku":"9781627031578","price":291.95,"currency_code":"CAD","in_stock":true},{"title":"Kobo eBook","offer_id":46187205132465,"sku":"fc495d66-02ba-3317-bafc-5462b24c15b2","price":141.89,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0655\/8980\/5233\/files\/1_6e8f415b-8684-4e67-96c6-18fc99b0739e.jpg?v=1762813469"},{"product_id":"controversies-in-treating-diabetes","title":"Controversies in Treating Diabetes: Clinical and Research Aspects","description":"\u003cp\u003eDiabetes Mellitus is an extremely common disorder and the number of patients is increasing every year.\u003cem\u003eControversies in Treating Diabetes: Clinical and Research Aspects\u003c\/em\u003eaddresses diabetes controversies, specifically in the etiology and management of the disease. With a thorough examination of the complications associated with diabetes, the volume covers commonly accepted forms of therapies and complications, as well as new and emerging advances, therapies and inadequacies in several standard treatments. Topics of emphasis include the metabolic syndrome, using insulin to treat Type 2, retinopathy, neuropathy, environmental stress, the diabetic foot, incretins, and the ADA and NCEP criteria for treating hyperlipidemia of diabetes.\u003c\/p\u003e\u003cp\u003eComprehensive and timely,\u003cem\u003eControversies in Treating Diabetes: Clinical and Research Aspects\u003c\/em\u003eis an essential reference for those treating and researching diabetes.\u003c\/p\u003e","brand":"None","offers":[{"title":"Paperback","offer_id":46186956456113,"sku":"9781617377310","price":175.5,"currency_code":"CAD","in_stock":true},{"title":"Hardcover","offer_id":46186956488881,"sku":"9781588297082","price":248.5,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0655\/8980\/5233\/files\/1_868f89a0-a8f3-4f99-a7ef-9eea63736b96.jpg?v=1764385909"},{"product_id":"autoimmunity-and-the-pathogenesis-of-diabetes","title":"Autoimmunity and the Pathogenesis of Diabetes","description":"It has been a challenge for us to edit this volume of Endocrinology and Metabo­ lism: Progress in Research and Clinical Practice. The topic of the pathogenesis of insulin-dependent, type I diabetes mellitus is particularly appropriate for this series, since advances in this area have been made, to a large extent, by applying state-of-the-art laboratory techniques to clinical samples. Over the last several years, a number of lines of evidence have been gathered, suggesting that classic type I diabetes mellitus results from the autoimmune des­ truction of pancreatic beta-cells in genetically susceptible individuals. This hypothesis is particularly appealing because it offers a rational approach to the prevention of diabetes by immunosuppression. We have tried to present a balanced, authoritative summary of the information currently available to support the autoimmune hypothesis for the pathogenesis of human type I diabetes, to place this information in historical perspective, to include relevant information from animal models of type I diabetes in which more invasive experimentation is ethical, and, finally, to update the reader on the current status of attempts to intervene in the progression of diabetes with immunosuppressive drugs. New York, New York Fredda Ginsberg-Fellner Robert C. McEvoy Contents Preface.. . . .. .. .. . . . . . . . . . . . . ... . . . . . . . . . . . .. . . . . . . .. . . . . v Contributors. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Xl . . . . . . . . . . . . . 1. The Autoimmune Hypothesis of Insulin-Dependent Diabetes: 1965 to the Present . . . . . . . . . . . . ..................... . . . . . .","brand":"None","offers":[{"title":"Paperback","offer_id":46186265804977,"sku":"9781461279204","price":80.5,"currency_code":"CAD","in_stock":true},{"title":"Kobo eBook","offer_id":46186265837745,"sku":"1bb90256-3d63-3812-9853-3a7cadb01257","price":64.49,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0655\/8980\/5233\/files\/1_00ce8e15-3da4-4dc6-a821-5849ae134a71.jpg?v=1762835282"}],"url":"https:\/\/www.indigo.ca\/collections\/endocrinology-metabolism.oembed","provider":"Indigo","version":"1.0","type":"link"}