{"product_id":"brain-function-and-dysfunction","title":"Brain Function and Dysfunction","description":"Alzheimer's Disease is rapidly increasing in prevalence. This pandemic of the post-industrial age wreaks havoc on the elderly people (some as young as 40), particularly in the richer and more powerful nations. With only a few weak hypotheses, its cause is not understood; all proposed medicines have either failed clinical trials or proven ineffective. In this book, I lay out a new, relatively stronger and more broad-based theory of dementia causation, exploring beyond Matsuyama's 1989 theory that held pervasive Microtubule collapse to be a key characteristic of dementia. In brief: Psychological functions are carried out by neurocircuits containing myriads of Dopaminergic and Norepic systems; due to excessive electrical signalling in \"dopamine-heavy\" types of brains -- the signal conducting micro-tubules break down, causing the neuronal collapse which characterizes dementia. More the signalling volume, more the stress (either mechanical and\/or thermal and\/or chemical stress), which proves fatal in the end.","brand":"None","offers":[{"title":"Couverture souple","offer_id":46410774216914,"sku":"9788192355979","price":10.67,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0655\/8980\/5233\/files\/1_ea95ea5f-6749-4277-bcb7-b03d0261d419.jpg?v=1762966143","url":"https:\/\/www.indigo.ca\/fr\/products\/brain-function-and-dysfunction","provider":"Indigo","version":"1.0","type":"link"}