{"product_id":"current-progress-of-mitochondrial-transplantation-a-new-paradigm-of-therapeutic-intervention-promoting-neuronal-re-generation-for-neurodegenerative-diseases-stroke-cns-injury-an-overview","title":"Current Progress of Mitochondrial Transplantation: A new paradigm of therapeutic intervention promoting Neuronal Re-generation for Neurodegenerative Diseases, Stroke, \u0026 CNS injury. An Overview","description":"\u003cp\u003eNeuronal Re-generation for Neurodegenerative Diseases, Stroke, \u0026amp; CNS injury. An Overview.\u003c\/p\u003e\n\u003cp\u003eMitochondria are the major source of intracellular adenosine triphosphate (ATP) and play an essential role in a plethora of physiological functions, including the regulation of metabolism and the maintenance of cellular homeostasis.\u003c\/p\u003e\n\u003cp\u003eMutations of mitochondrial DNA, proteins and impaired mitochondrial function have been implicated in the neurodegenerative diseases, stroke and injury of the central nervous system (CNS).\u003c\/p\u003e\n\u003cp\u003eThe dynamic feature of mitochondrial fusion, fission, trafficking and turnover have also been documented in these diseases.\u003c\/p\u003e\n\u003cp\u003eA major bottleneck of traditional approach to correct mitochondria-related disorders is the difficulty of drugs or gene targeting agents to arrive at specific sub-compartments of mitochondria.\u003c\/p\u003e\n\u003cp\u003eMoreover, the diverse nature of mitochondrial mutations among patients makes it impossible to develop one drug for one disease.\u003c\/p\u003e\n\u003cp\u003eTo this end, mitochondrial transplantation presents a new paradigm of therapeutic intervention that benefits neuronal survival and regeneration for;\u003c\/p\u003e\n\u003cp\u003eNeurodegenerative diseases,\u003cbr\u003e\nStroke, and\u003cbr\u003e\nCNS injury.\u003c\/p\u003e\n\u003cp\u003eSupplement of healthy mitochondria to damaged neurons has been reported to promote neuronal viability, activity and neurite re-growth.\u003c\/p\u003e\n\u003cp\u003eThus an attempt has been made in this Booklet to provide an overview of the recent advance and development on emerging mitochondrial therapy.\u003c\/p\u003e\n\u003cp\u003e…Dr. H. K. Saboowala.\u003c\/p\u003e\n\u003cp\u003eM.B.(Bom) .M.R.S.H.(London)\u003c\/p\u003e","brand":"None","offers":[{"title":"Kobo eBook","offer_id":46721203765458,"sku":"c5640c46-da8e-387d-957c-21b85130c389","price":6.79,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0655\/8980\/5233\/files\/image_425d1c51-718c-4a12-81d4-683be9034b6e.jpg?v=1772213403","url":"https:\/\/www.indigo.ca\/products\/current-progress-of-mitochondrial-transplantation-a-new-paradigm-of-therapeutic-intervention-promoting-neuronal-re-generation-for-neurodegenerative-diseases-stroke-cns-injury-an-overview","provider":"Indigo","version":"1.0","type":"link"}