The reprint highlights different forms of cardiomyopathy, such as RBM20, filamin C, and lamin A/C cardiomyopathy. Diagnostic and new treatment options are presented in arrhythmogenic, hypertrophic, dilated, and restrictive cardiomyopathy. As a special form of cardiomyopathy, the value of ajmaline testing in Brugada syndrome is highlighted. This reprint provides new information on the common forms of cardiomyopathy and highlights new approaches.