The book starts with a detailed description of the optimal way to lose weight and information on how to keep it off. However, you are strongly advised to read the subsequent chapters as referenced in Chapter 1. The author has noted that his patients find it both helpful and liberating to have an understanding of the regulation of body weight, of the causes of obesity, the health problems that obesity causes and the biological mechanisms that make it difficult to maintain weight loss. All of the information provided in this book is backed by published scientific evidence. References are provided at the end of the book that can be freely accessed through searchable medical databases such as PubMed or Google Scholar. For the lay reader, much of what is written in scientific articles may be overly technical, however many can be helped in the interpretation and meaning of the information by their family doctor who will play a key role in their weight loss journey.