In this issue ofNeuroimaging Clinics, guest editors Drs. Natalia Nagornaya and Gaurav Saigal bring their considerable expertise to the topic ofImaging of Acute Encephalopathies . Top experts discuss hypoxic ischemic encephalopathy; stroke-like syndromes in encephalopathy; metabolic derangement and vitamin deficiencies in encephalopathy; vascular and hematologic disorders; autoimmune, paraneoplastic, or idiopathic disorders in encephalopathy; and more.