It is sometimes assumed that individuals with congenital heart disease have a diminished quality of life. However, this does not fit with clinical impressions. A large portion of these persons have a good quality of life. The paradox of having physical limitations, albeit experiencing an excellent quality of life urges to raise some questions: How well are studies on quality of life in congenital heart disease conducted? How is quality of life being measured? Can patients indicate what is important for their quality of life? How can a good quality of life in persons with heart defects be explained? This book describes the results of different studies that have been conducted in this respect. This book is a source for clinicians and researchers to understand how persons with congenital heart disease can have an excellent quality of life. Furthermore, this book can be a source of support for patients and parents to value a good quality of life, irrespective the heart condition.