Sarcopenia refers to the aging-related muscle wasting and weakness which involves a degenerative loss of skeletal muscle mass, quality and strength. It is a condition characterized by muscular atrophy. Exercise level, nutrition, and co-morbidities all influence the rate of muscle loss. Changes in muscle synthesis signaling pathways are linked to the loss of muscle. Sarcopenia can impair a person's capacity to perform daily tasks such as walking, climbing stairs and lifting objects. It is linked to severe comorbidities, including obesity, osteoporosis, type 2 diabetes and insulin resistance. Sarcopenia can be prevented and delayed by leading an active lifestyle and engaging in physical activity. This book is compiled in such a manner, that it will provide in-depth knowledge on the impact of age-related muscle wasting and weakness associated with sarcopenia. It aims to shed light on some of the unexplored aspects of this disease. A number of latest researches have been included to keep the readers up-to-date with the global concepts in this medical condition.