Emily Lime and her equally palindromic dog, Otto, live in Williamsburg, Brooklyn (zip code 11211), in a warm community of friends and fellow artists. Her life becomes more complicated when she falls in love with Marcus, a dog-walker and fellow Scrabble nut, whose father is Emily's shady ex-husband who wants the lovable Emily dead. A mystery unravels, a valuable lost cache of paintings is found, and Emily's life changes in ways she could not have anticipated.