Aiming to develop a less studied literary genre, this book provides a well-rounded picture of spiritual and physical diseases and their remedies as they were ingrained in the imagination and practices of Middle Eastern Abrahamic cultures, with a special emphasis of Christian communities (Greeks/Byzantines, Syrians, Armenians, Georgians, Ethiopians). The volume traces traditions dealing with the onset of a disease in the body and soul, the search for remedy, the maintenance of healing, and the engagement of these processes with faith—either through their affirmation in the public sphere or remaining within the personal framework, as in monastic traditions. A recurring presence in religious literature and the history of the intellectual world, the confrontation between disease and healing may well still be current for our modern understanding of the paths to seeking and maintaining the health of one’s body and soul, without excluding the factor of faith as a core principle.