Nestled deep within the Northern Canadian wilderness, St. Camillus Consumption Sanitarium serves as a haunting warning; a place where penitence and prayer negate the use of modern medicine, and isolation is thought to heal both the lungs and the soul of the infirm. Margaret Sanderson, a young Métis woman burdened by a tumultous past, works dilligently to ease the patients of St. Camillus into death whilst trying to solve a mystery that has plagued her for a nearing decade. With the arrival of Red McIntyre, a young Irishman with fiery hair and a personality to match, comes a sudden onset of otherworldly activity that draws Margaret to the charming patient, igniting an unlikely friendship. Red sees the same twisted figures, hears the same phantom voices and possesses the same odd brand upon his wrist. Margaret finds solace in the fact that, despite what the other nurses might think, she is not crazy. And she is not alone. Then Red McIntyre dies. What happens next is the story of 'White Plague.'