Eleuterio F. Toro is currently a n Emeritus Professor of Mathematics at the University of Trento, Italy. For several decades his research has focused on the development of computational methods for solving partial differential equations, with special emphasis on hyperbolic balance laws and applications to environmental and industrial problems . For the past fifteen years he has been investigating the bio physic al aspects of neurodegenerative diseases and its relation to the altered dynamical interaction of multi- materials in the central nervous system (arterial blood, venous blood, interstitial fluid, cerebrospinal fluid, the brain parenchyma and the newly discovered brain g lymphatic system). Professor Toro has written numerous research articles and books, including the standard work Riemann Solvers and Numerical Methods for Fluid Dynamics: A Practical Introduction, published by Springer.