Twenty years ago, a group of students from Clemson University planted a large number of Magnolia Trees on a large barrier island off of the Southern coast of South Carolina. Now the secluded barrier island is covered with beautiful Southern Magnolia trees. The isolated island is accessible only by boat, but that is about to change. A long bridge is being built to the island. This is going to be an island for the rich and famous. A hospital with state of the art equipment has been built on the island. Top physicians have been hired to treat the rich patients who come to the Magnolia Island Hospital from all over the world. Dr. Susan Pearson from Johns Hopkins Hospital comes to the island for a short vacation, but is so impressed, she decides to stay. Dr. Bradley Clark, the hospital administrator runs the hospital with an iron fist. The plot becomes more complex. Multiple problems occur as some of the best doctors in the world take care of the demanding rich and famous patients.