Tai Tsun Wu (1933-2024) passed away in July 2024 at the age of 90, leaving behind a towering legacy that continues to shape the frontiers of theoretical and mathematical physics. A prodigious talent, he earned his PhD in applied physics from Harvard University at the age of 22, and was soon named a Junior Fellow of the Harvard Society of Fellows — before beginning a professorship career at Harvard that would span more than six decades.Renowned for his pioneering research in antenna theory, statistical physics, Higgs physics, and perturbative quantum field theory, Wu authored over 400 scientific papers across more than seventy years. His landmark contributions — ranging from the Wu-Yang monopole and monopole harmonics, to the first prediction of rising total cross-sections in high-energy scattering and many precision calculations in theoretical high energy physics — reflect a career devoted to unifying the physical and mathematical worlds.Honored with numerous accolades — including the Dannie Heineman Prize for Mathematical Physics, the Alexander von Humboldt Senior Scientist Award, and election to the American Academy of Arts and Sciences — Wu remained intellectually active until the very end, publishing his final paper at the age of 89. In this work, he introduced the "Basic Standard Model", a streamlined reformulation of the Standard Model of particle physics that reduces the number of fundamental parameters and provides a novel theoretical relation between the three gauge coupling constants. Within less than a year from its publication to his passing, the paper garnered over 13,000 downloads, drawing wide attention.This memorial volume celebrates the life and work of Tai Tsun Wu, whose journey — from a home-schooled boy in Shanghai to Gordon McKay Professor of Applied Physics and Professor of Physics at Harvard — was marked by brilliance, wonder, and resilience.Featuring reflections from family, heartfelt letters from collaborators and students, along with archival photos and a curated selection of some of his most influential publications, this Memorial Volume offers a rare glimpse into both the mind and heart of Prof. Tai Tsun Wu. It honors not only his scientific legacy but also the cherished memories of his pioneering work across diverse fields, reflecting the humility, warmth, and generosity that enriched his remarkable intellectual journey.