In this issue ofClinics in Sports Medicine, guest editors Drs. Rachel Frank, Brian J. Cole, Andrew S. Bi, and Nicholas Tsouris bring their considerable expertise to the topic ofOrthobiologics in Sports Medicine . Top experts discuss areas such as traditional injection therapy for OA: do they work and are they safe?; platelet-based injections for knee OA; BMA and BMC for the treatment of knee OA; adipose and MFAT for the treatment of knee OA; orthobiologics for ligament injuries; biologics for bone injuries; and more.