No higher or more imperative duty confronts the State and institutions of learning than that of encouraging, in every possible manner, the prosecution of studies which promise to result in the determination of the sources of rational thought and action; but it is evident that the main burden of the work must be borne by the medical profession, from whose ranks must come the leaders of any movement which has for its object the prevention and cure of the diseases characterized by defective or perverted functioning of the brain.

In writing this book I have made no attempt to compose an exhaustive treatise; my main object has been to call atten tion to that aspect of the subject which is in accord with the results of observations as they are conducted to-day at the bed side and in the laboratory; and while presenting the different views of leading authorities in a manner readily to be compre hended by students of this important branch of medicine, to stimulate to greater activity the interest in the investigation of problems in the solution of which will be found the means of increasing the brain power of the nation.

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