A sarcoma is the cancer of the transformed cells of mesenchymal origin. All malignant tumors of cancellous bone, fat, cartilage, muscle, vascular or hematopoietic tissues are considered sarcomas. These are named based on the tissue of origin and are assigned a grade depending on the presence of cellular and subcellular characteristics that are associated with malignant biological behavior as well as their frequency. High-grade tumors can undergo metastasis and therefore need aggressive treatment. Surgery is important in the treatment of sarcomas. Other treatments such as chemotherapy and radiation therapy may also be administered, whether before or after surgery. These can improve prognosis and increase chances of survival. This book unravels the recent studies in sarcoma. It unfolds the innovative aspects in the management of sarcoma which will be crucial for the progress of oncology in the future. It will help new researchers by foregrounding their knowledge in this medical condition.