Twenty-eight years ago the late Sir john Burdon Sanderson described one of the aims of Physiology as the acquirement of an exact knowledge of the chemical and physical processes of animal life. The recent history of physiological progress shows that investigations confined to the study of physical and chemical processes have been the most fruitful source of physiological advance, and it is principally the exact chemical study of the substances found in animals and plants which has enabled the physiologist to make this advance.

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