Viral hepatitis is a type of viral infection that causes damage and inflammation to the liver. This infection has a complex pathology, and it may manifest in acute or chronic forms. In its acute manifestation, it breaks out rapidly, whereas, in its chronic manifestation, it spreads progressively. The most common causes of viral hepatitis include the five unrelated hepatotropic viruses, namely hepatitis A, B, C, D, and E. Viral hepatitis can be spread by blood, body fluids, and through contaminated water and food. Blood tests and a physical examination are commonly used to diagnose viral hepatitis such as hepatitis A, B and C. The treatment of acute viral hepatitis includes relieving symptoms, relaxing, and drinking plenty of fluids. Chronic viral hepatitis is treated with antiviral drugs and preventative measures to stop further liver damage. Such selected concepts that redefine the diagnosis, pathophysiology and treatment of viral hepatitis have been presented in this book. A number of latest researches have been included to keep the readers up-to-date with the global concepts related to viral hepatitis.